Landholders in central and south east Queensland have been urged to be vigilant, following a major increase in mouse numbers in the region.
Good seasonal conditions, coupled with food availability in cropping regions, is thought to behind the increase.
Regional towns west of Maryborough have been heavily impacted, with some householders in North Burnett catching 30 and 40 mice per night in their houses.
One landholder in Gayndah caught over 1000 mice in water traps in a space of three days.
CSIRO researcher and mouse expert Steve Henry said mouse outbreaks were having an impact on un-harvested Summer crops.
"There is quite a bit of baiting going on, particularly in autumn crops and in some cases in the freshly sown winter crops," Mr Henry said.
"Apparently a population of mice started at the Boyne Valley about a month ago and has moved on into Monto.
"I'm now hearing reports of mice outbreaks impacting un-harvested summer crops, including mung beans, soy beans and recently planted winter crops."
Mr Henry said mice population outbreaks generally occur where there is food, shelter and good moisture in the system.
"These three factors support breeding activity," he said.
"We're seeing high numbers from a large number of areas that seem to tied to paddock history.
"In scenarios where you've had a big barley crop and you've had some head loss prior to the headers going through, then at that point, you actually get a buildup in the number of mice."
Local farmers in affected areas are now taking action as they sow the subsequent crop.
"Up in Queensland it's a bit different with a dual cropping system," Mr Henry said.
"With a summer and winter crop, you're putting food into the system more often and you're getting those localised kind of outbreaks where mice are responding to food availability.
"There isn't a consistently large outbreak across Queensland cropping systems but more of this sort of patchy sorts of outbreaks."
Mr Henry said the key message to farmers is that they need to get out and go for a walk in their paddocks to see signs of mice.
"If they're seeing concerning numbers of mice, they need to be prepared to bait them either as they're sowing their winter crop or take action to protect their un-harvested summer crops," he said.
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