Roma has recorded two confirmed cases of COVID-19, while Blackall has confirmed one.
South West Hospital and Health Service's chief executive Dr Anthony Brown said the Roma cases were related, double vaccinated, and being cared for at home.
They had travelled in Queensland before returning to Roma and testing positive.
"If you are displaying any COVID-19 symptoms, no matter how mild, you should always get tested," Dr Brown said.
"Symptoms include: Fever, sore throat, runny nose, cough, shortness of breath, fatigue, diarrhoea, vomiting, nausea or lack of taste or smell.
"Testing is available at Roma Hospital and at all our health facilities in the south west."
Dr Brown said 86.9 per cent of eligible residents in the south west aged 12 and over were fully vaccinated, and 93.6 per cent have had one dose, which he said was the "highest rate of any health service in the state".
"Our First Nations vaccination rate also is the highest in the state, with 85 per cent of eligible First Nations residents aged 12 years and older being fully vaccinated with both doses of vaccine and 97.3 per cent who have had at least one dose," Dr Brown said.
The Blackall case is also double vaccinated, and being cared for at home after returning from New South Wales.
Central West Hospital and Health Service chief executive Mr Anthony West said the patient had "limited contact" while in Blackall and there was minimal risk to the broader community, however contract tracing is underway.
Anyone in Blackall or the surrounding area wanting or needing a COVID-19 should call ahead to the Blackall Hospital on 4650 7700.
"The Blackall-Tambo Regional Council is the most fully-vaccinated local government area in the Central West with 92.7 per cent of all eligible residents aged 12 years and older now fully vaccinated and 99.1 per cent having received at least one dose," Mr West said.
"Across the Central West as a whole, 86.8 per cent of all eligible residents aged 12 years and older are now fully vaccinated with two doses of vaccine and 93.3 per cent have had at least one dose."
For more information or to check contact tracing sites, please visit the Queensland Government website here.
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